The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2020

Filed:

Sep. 26, 2014
Applicants:

Kevin J. Edgar, Blacksburg, VA (US);

Xiangtao Meng, Blacksburg, VA (US);

John Matson, Blacksburg, VA (US);

Inventors:

Kevin J. Edgar, Blacksburg, VA (US);

Xiangtao Meng, Blacksburg, VA (US);

John Matson, Blacksburg, VA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08B 3/16 (2006.01); C08B 3/00 (2006.01); C08B 37/02 (2006.01); C08B 37/00 (2006.01); A61K 47/38 (2006.01); C08B 3/14 (2006.01);
U.S. Cl.
CPC ...
C08B 3/16 (2013.01); A61K 47/38 (2013.01); C08B 3/00 (2013.01); C08B 3/14 (2013.01); C08B 37/0018 (2013.01); C08B 37/0021 (2013.01);
Abstract

Methods for the cross-metathesis of polysaccharides with one or more olefin-terminated side chains and cross-metathesized products are described. In an exemplary embodiment, a method for the synthesis of cellulose ω-carboxyesters via olefin cross-metathesis is described. Conditions of the reactions were relatively mild and the olefin-substituted polysaccharides and the appropriate monomeric olefin partners appear to follow Grubbs rules as summarized herein. The compounds and methods may be useful for structure-property studies, particularly those aimed at developing polymers for drug delivery, such as for controlled-release drug delivery systems, controlled-release coatings, increasing bioavailability of drugs, and maintaining drug supersaturation in the GI tract.


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