The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2020
Filed:
Sep. 20, 2017
Applicants:
Merck Patent Gmbh, Darmstadt, DE;
Pfizer Inc., New York, NY (US);
Inventors:
Assignees:
Merck Patent GmbH, Darmstadt, DE;
Pfizer Inc., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); G01N 33/574 (2006.01); C07K 16/30 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/30 (2013.01); G01N 33/57492 (2013.01); C07K 2317/10 (2013.01); C07K 2317/20 (2013.01); C07K 2317/34 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); G01N 2333/70532 (2013.01); G01N 2333/70596 (2013.01);
Abstract
The present invention provides for an antibody or antigen-binding fragment thereof which binds to an epitope within human PD-L1 with high specificity and reproducibility. The inventive antibody or antigen-binding fragment thereof may be used in assessing PD-L1 expression in tissue samples to aid in patient stratification. The present invention further provides methods of producing the inventive antibody.