The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2020

Filed:

Sep. 19, 2018
Applicant:

Icb International, Inc., La Jolla, CA (US);

Inventors:

Ram S. Bhatt, San Diego, CA (US);

Rishi S. Bhatt, San Diego, CA (US);

Assignee:

ICB INTERNATIONAL, INC., La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); A61K 49/00 (2006.01); A61K 49/16 (2006.01); C07K 14/00 (2006.01); A61K 38/00 (2006.01); C07K 14/475 (2006.01); C07K 14/48 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01); A61K 47/68 (2017.01); A61K 47/69 (2017.01); A61K 51/02 (2006.01); A61K 49/18 (2006.01); A61K 51/10 (2006.01); A61K 49/08 (2006.01); A61K 51/12 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 47/6843 (2017.08); A61K 47/6933 (2017.08); G01N 33/6857 (2013.01); G01N 33/6896 (2013.01); A61K 38/00 (2013.01); A61K 39/395 (2013.01); A61K 47/6811 (2017.08); A61K 47/6817 (2017.08); A61K 47/6889 (2017.08); A61K 47/69 (2017.08); A61K 47/6921 (2017.08); A61K 47/6923 (2017.08); A61K 47/6925 (2017.08); A61K 47/6927 (2017.08); A61K 47/6931 (2017.08); A61K 47/6935 (2017.08); A61K 47/6939 (2017.08); A61K 49/005 (2013.01); A61K 49/0017 (2013.01); A61K 49/0019 (2013.01); A61K 49/0058 (2013.01); A61K 49/085 (2013.01); A61K 49/16 (2013.01); A61K 49/18 (2013.01); A61K 51/02 (2013.01); A61K 51/1093 (2013.01); A61K 51/12 (2013.01); A61K 2039/505 (2013.01); A61P 25/00 (2018.01); C07K 2317/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/22 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/569 (2013.01); C07K 2317/60 (2013.01); C07K 2317/62 (2013.01); C07K 2317/64 (2013.01); C07K 2317/66 (2013.01); C07K 2318/00 (2013.01); C07K 2318/10 (2013.01); C07K 2318/20 (2013.01); G01N 2800/28 (2013.01); G01N 2800/2814 (2013.01); G01N 2800/2821 (2013.01);
Abstract

Blood-brain barrier permeable peptide compositions that contain variable antigen binding domains from camelid and/or shark heavy-chain only single-domain antibodies are described. The variable antigen binding domains of the peptide compositions bind to therapeutic and diagnostic biomarkers in the central nervous system, such as the amyloid-beta peptide biomarker for Alzheimer's disease. The peptide compositions contain constant domains from human IgG, camelid IgG, and/or shark IgNAR. The peptide compositions include heavy-chain only single-domain antibodies and compositions with one or more variable antigen binding domain bound to one or more constant domains.


Find Patent Forward Citations

Bhatt, Ram. (2020). Blood-brain barrier permeable peptide compositions comprising a vab domain of an anti-amyloid-beta camelid single-domain heavy-chain only antibody (U.S. Patent No. 10738109). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10738109

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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