The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2020
Filed:
Oct. 05, 2018
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Richard Thomas Lewis, Missouri City, TX (US);
Philip Jones, Houston, TX (US);
Alessia Petrocchi, Houston, TX (US);
Naphtali Reyna, Arlington, TX (US);
Matthew Hamilton, Missouri City, TX (US);
Michael J. Soth, Sugar Land, TX (US);
Timothy Heffernan, Sugar Land, TX (US);
Michelle Han, Houston, TX (US);
Jason P. Burke, Houston, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); A61K 31/501 (2006.01); A61K 45/06 (2006.01); C07D 403/14 (2006.01); C07D 401/14 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/4439 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/501 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01);
Abstract
Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.