The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2020
Filed:
Feb. 26, 2019
1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-i-yl) ureas as p38 mapkinase inhibitors
Applicant:
Respivert Limited, Buckinghamshire, GB;
Inventors:
Kazuhiro Ito, Wallington, GB;
Catherine Elisabeth Charron, London, GB;
John King-Underwood, Pendock, GB;
Stuart Thomas Onions, Nottingham, GB;
Alistair Ian Longshaw, Nottingham, GB;
Rudy Broeckx, Beerse, BE;
Walter Filliers, Beerse, BE;
Alex Copmans, Beerse, BE;
Assignee:
Respivert Limited, Buckinghamshire, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/4155 (2006.01); C07D 491/10 (2006.01); A61K 31/215 (2006.01); A61K 31/351 (2006.01); A61K 31/513 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/215 (2013.01); A61K 31/351 (2013.01); A61K 31/4155 (2013.01); A61K 31/506 (2013.01); A61K 31/513 (2013.01); C07D 491/10 (2013.01); C07B 2200/13 (2013.01); Y02A 50/406 (2018.01);
Abstract
There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and COPD.