The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2020
Filed:
Sep. 07, 2017
Takeda Pharmaceutical Company Limited, Chuo-ku, Osaka-shi, Osaka, JP;
Toshitake Kobayashi, Kanagawa, JP;
Morihisa Saitoh, Kanagawa, JP;
Yasufumi Wada, Kanagawa, JP;
Nobuyuki Negoro, Kanagawa, JP;
Masashi Yamasaki, Kanagawa, JP;
Takahiro Tanaka, Kanagawa, JP;
Naomi Kitamoto, Kanagawa, JP;
Takeda Pharmaceutical Company Limited, Osaka, JP;
Abstract
Provided is a compound, such as ethyl 6-((2-chloro-4-fluorobenzyl)sulfonyl) -3-hydroxycyclohex-1-ene-1-carboxylate or an optical isomer thereof, having a superior Toll-like receptor 4 (TLR4) signaling inhibitory action, which may be useful as a prophylactic or therapeutic drug for diseases such as autoimmune diseases and/or inflammatory diseases, or chemotherapy-induced peripheral neuropathy (CIPN), chemotherapy-induced neuropathic pain (CINP), liver failure, and ischemia reperfusion injury (IRI).