The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2020

Filed:

May. 20, 2016
Applicants:

Kaushik J. Dave, Edison, NJ (US);

Yulian Zhang, Acton, MA (US);

Inventors:

Kaushik J. Dave, Edison, NJ (US);

Yulian Zhang, Acton, MA (US);

Assignee:

Actinium Pharmaceuticals, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/10 (2006.01); C07K 16/28 (2006.01); A61K 47/68 (2017.01); A61P 35/02 (2006.01); A61K 31/427 (2006.01); A61K 31/7036 (2006.01); A61M 5/14 (2006.01); A61M 5/142 (2006.01); A61B 6/00 (2006.01); A61K 9/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/1027 (2013.01); A61K 31/427 (2013.01); A61K 31/7036 (2013.01); A61K 47/6803 (2017.08); A61K 47/6809 (2017.08); A61K 47/6849 (2017.08); A61K 47/6867 (2017.08); A61K 51/1069 (2013.01); A61M 5/14 (2013.01); A61P 35/02 (2018.01); C07K 16/2803 (2013.01); C07K 16/289 (2013.01); C07K 16/2887 (2013.01); A61B 6/4057 (2013.01); A61K 9/0019 (2013.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61M 5/142 (2013.01); A61M 2005/1403 (2013.01);
Abstract

A patient specific therapeutic composition provided in a single dose container, the total volume of which may be administered to a patient in a single treatment session. The composition includes a monoclonal antibody having a labeled fraction and an unlabeled fraction, and a pharmaceutically acceptable carrier. The label may be any of a radioisotope or a drug such as a chemotherapeutic or cytotoxic agent. The amount of the monoclonal antibody and any conjugated label molecule may depend on at least one patient specific parameter selected from a patient weight, a patient age, a patient height, a patient gender, a patient medical condition, and a patient medical history. Methods of administration, production, and articles of manufacture comprising the patient specific therapeutic composition are also disclosed.


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