The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2020

Filed:

Jun. 27, 2019
Applicant:

Virginia Commonwealth University, Richmond, VA (US);

Inventor:

Jason A. Carlyon, Richmond, VA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/40 (2006.01); C07K 16/12 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0233 (2013.01); A61K 39/40 (2013.01); C07K 16/1246 (2013.01); G01N 33/56911 (2013.01); G01N 33/56983 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6081 (2013.01); A61K 2039/70 (2013.01); C07K 2317/76 (2013.01); G01N 2333/195 (2013.01); G01N 2333/29 (2013.01); G01N 2469/10 (2013.01); G01N 2800/42 (2013.01); Y02A 50/403 (2018.01);
Abstract

surface proteins Asp14 and OmpA and homologous genes from Anaplasmatacaea family members are used in compositions suitable for vaccines to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. Asp14 and/or OmpA proteins or peptide fragments may be used in combination with other Anaplasmatacaea surface proteins to elicit an immune response. Furthermore, antibodies to Asp14 and/or OmpA proteins can be used in diagnostic methods to determine whether an individual has contracted an Anaplasmatacaea infection. Because of the conserved invasin domains in the surface proteins, a wide range of Anaplasmatacaea infections may be diagnosed, treated or prevented using compositions of the invention.


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