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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10736929 B1

PDFFull Text
Date of Patent:
Aug. 11, 2020

Filed:

Oct. 10, 2016

Method for preparing herbal composition having increased fat-solublepolyphenol content, herbal composition prepared thereby and use thereof

Applicant:

Korea Atomic Energy Research Institute, Daejeon, KR;

Inventors:

Sung-Kee Jo, Jeollabuk-do, KR;

Hae Ran Park, Jeollabuk-do, KR;

Uhee Jung, Gyeonggi-do, KR;

Ho Yong Lee, Gyeonggi-do, KR;

Hyang Hee Cho, Gwangju, KR;

Assignee:

KOREA ATOMIC ENERGY RESEARCH INSTITUTE, Daejeon, KR;

Attorney:

Klarquist Sparkman, LLP

Primary Examiner:

Michael Barker

Assistant Examiner:

Randall Winston

Int. Cl.
CPC ...
A61K 36/23 (2006.01); A61K 36/65 (2006.01); A61K 36/00 (2006.01); A61K 36/232 (2006.01); A61K 31/352 (2006.01); A61K 31/7048 (2006.01); A61K 36/234 (2006.01); A23L 33/105 (2016.01); A61P 35/00 (2006.01); A61P 37/04 (2006.01); A23L 33/10 (2016.01); A61K 31/192 (2006.01); B01D 11/02 (2006.01);
U.S. Cl.
CPC ...
A61K 36/232 (2013.01); A23L 33/10 (2016.08); A23L 33/105 (2016.08); A61K 31/192 (2013.01); A61K 31/352 (2013.01); A61K 31/7048 (2013.01); A61K 36/234 (2013.01); A61K 36/65 (2013.01); A61P 35/00 (2018.01); A61P 37/04 (2018.01); B01D 11/0288 (2013.01); A23V 2002/00 (2013.01); A61K 2236/00 (2013.01); A61K 2236/331 (2013.01); A61K 2236/333 (2013.01);
Abstract

The present invention relates to a method for preparing an herbal composition with increased fat-soluble polyphenols, an herbal composition prepared by the method, and a use of the composition. The herbal composition with increased fat-soluble polyphenols of the present invention is characterized by the significantly increased content of fat-soluble polyphenols including decursin, compared with the herbal composition of comparative example, and also demonstrates a significant anti-oxidative activity, immune cell activating effect, and cancer cell growth inhibitory effect, significantly reduces renal toxicity and liver toxicity induced by the anticancer agent cisplatin back so as to be almost normal condition, and significantly inhibits the intestinal crypt loss caused by irradiation, compared with the herbal composition of comparative example. Therefore, the herbal composition with increased fat-soluble polyphenols of the present invention can be effectively used as a composition for cancer treatment, an anti-cancer adjuvant, a composition for enhancing immune function, a composition for protecting a living body, and a composition for preventing side effects of cancer treatment.

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