The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2020
Filed:
Jun. 09, 2016
Applicants:
Children's Medical Center Corporation, Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
Inventors:
Leonard I. Zon, Wellesley, MA (US);
Trista E. North, Newton Center, MA (US);
Wolfram Goessling, Chestnut Hill, MA (US);
Assignees:
CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US);
THE GENERAL HOSPITAL CORPORATION, Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/201 (2006.01); A61K 31/404 (2006.01); A61K 31/5575 (2006.01); A61K 31/557 (2006.01); A61K 31/41 (2006.01); A61K 31/558 (2006.01); A61K 31/5585 (2006.01); A61K 31/655 (2006.01); A61K 33/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5575 (2013.01); A61K 31/201 (2013.01); A61K 31/404 (2013.01); A61K 31/41 (2013.01); A61K 31/557 (2013.01); A61K 31/558 (2013.01); A61K 31/5585 (2013.01); A61K 31/655 (2013.01); A61K 33/14 (2013.01);
Abstract
The present invention provides for compositions and methods for modulating tissue growth using tissue growth modulators, which are agents that either enhance or inhibit tissue growth as desired by a particular indication by modulating the PG or Wnt signaling pathways, or employing modulators of both PG and Wnt signaling pathways for a synergistic effect or highly selective effect.