The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2020
Filed:
Oct. 12, 2008
Ulrich H. Von Andrian, Chestnut Hill, MA (US);
Omid C. Farokhzad, Chestnut Hill, MA (US);
Robert S. Langer, Newton, MA (US);
Tobias Junt, Schorndorf, DE;
Elliott Ashley Moseman, Jamaica Plain, NY (US);
Liangfang Zhang, San Diego, CA (US);
Pamela Basto, Somerville, MA (US);
Matteo Iannacone, Boston, MA (US);
Frank Alexis, Greenville, SC (US);
Ulrich H. Von Andrian, Chestnut Hill, MA (US);
Omid C. Farokhzad, Chestnut Hill, MA (US);
Robert S. Langer, Newton, MA (US);
Tobias Junt, Schorndorf, DE;
Elliott Ashley Moseman, Jamaica Plain, NY (US);
Liangfang Zhang, San Diego, CA (US);
Pamela Basto, Somerville, MA (US);
Matteo Iannacone, Boston, MA (US);
Frank Alexis, Greenville, SC (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
The Children's Medical Center Corporation, Boston, MA (US);
Abstract
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at least one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof.