The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2020

Filed:

Sep. 03, 2014
Applicant:

Georgia Tech Research Corporation, Atlanta, GA (US);

Inventors:

Matthew Joseph Mistilis, Atlanta, GA (US);

William Christopher Edens, Atlanta, GA (US);

Andreas Sebastian Bommarius, Atlanta, GA (US);

Mark Prausnitz, Atlanta, GA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 39/165 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); A61K 39/145 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0021 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/165 (2013.01); C12N 7/00 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/70 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16234 (2013.01); C12N 2760/16334 (2013.01); C12N 2760/18434 (2013.01);
Abstract

Formulations and methods are provided for stabilizing antigens in dry solid vaccines. One aspect relates to dry solid formulations of influenza vaccines including one or more excipients identified as imparting stability to influenza antigens. Another aspect relates to dry solid formulations of measles vaccines including one or more excipients identified as imparting stability to a measles antigen. The formulations may be in a form suitable for reconstitution in a physiologically acceptable liquid vehicle to form an injectable solution or suspension for administration to a patient or in the form of dissolvable microneedles or coated microneedles.


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