The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
Jun. 04, 2014
Indevr, Inc., Boulder, CO (US);
Kathy Rowlen, Boulder, CO (US);
Laura R. Kuck, Boulder, CO (US);
INDEVR, INC., Boulder, CO (US);
Abstract
A universal array for multiplexed quantification of variable hemagglutinin such as subcomponents of multivalent annual influenza vaccines that is robust to variations in proteins such as mutations and is capable of quantifying degradation of proteins. Universal capture array () comprises one or more substrates () and a low-density microarray () of sub-arrays () comprising spots (-). The microarray () is contacted with one or more targets () at one or more unknown concentrations, and bound complexes () are formed and subsequently quantified with a suitable method. Quantified signals are compared to calibration curves to obtain one or more unknown concentrations and/or quantify degradation of the one or more targets (). Other embodiments are described and shown.