The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2020

Filed:

Oct. 30, 2015
Applicants:

Ewha University—industry Collaboration Foundation, Seoul, KR;

Korea Advanced Institute of Science and Technology, Daejeon, KR;

Inventors:

Hyukjin Lee, Seoul, KR;

Haeshin Lee, Daejeon, KR;

Ho Yeon Lee, Daejeon, KR;

Il Young Jung, Sejong, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6853 (2018.01); B01L 7/00 (2006.01); C12M 1/38 (2006.01); C12Q 1/68 (2018.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6853 (2013.01); B01L 3/00 (2013.01); B01L 3/502707 (2013.01); B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); B01L 7/00 (2013.01); C12M 1/38 (2013.01); C12Q 1/68 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/16 (2013.01); Y02A 50/451 (2018.01); Y02A 50/54 (2018.01); Y02A 50/58 (2018.01);
Abstract

The present invention provides facile and accurate molecular diagnosis of disease-specific genes capable of the naked eye detection through amplifying the target genes to selectively block the fluid path in a microfluidic device. Specifically, the present invention includes an isothermal amplification of target genes through a rolling circle amplification, a microfluidic device for detecting pathogen genes, and a detection method using the same. Therefore, the present invention can conveniently detect a single target gene, such as a single pathogen, or at the same time, several target genes, such as several pathogens, without complicated mechanical equipment.


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