The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2020

Filed:

Jun. 20, 2019
Applicant:

Codexis, Inc., Redwood City, CA (US);

Inventors:

Haibin Chen, Beijing, CN;

Yong Koy Bong, Singapore, SG;

Fabien L. Cabirol, Dusseldorf, DE;

Anupam Gohel Prafulchandra, Bekasi, ID;

Tao Li, Cincinnati, OH (US);

Jeffrey C. Moore, Westfield, NJ (US);

Martina Quintanar-Audelo, Edinburgh, GB;

Yang Hong, Singapore, SG;

Steven J. Collier, Concord, MA (US);

Derek Smith, Singapore, SG;

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 11/10 (2006.01); C12P 17/12 (2006.01); C12P 17/18 (2006.01); C12N 9/02 (2006.01); C12P 13/24 (2006.01); C12P 13/04 (2006.01);
U.S. Cl.
CPC ...
C12P 17/12 (2013.01); C12N 9/0071 (2013.01); C12P 13/04 (2013.01); C12P 13/24 (2013.01); C12P 17/188 (2013.01); C12Y 114/11002 (2013.01); Y02P 20/52 (2015.11);
Abstract

The present disclosure provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.


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