The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
May. 06, 2014
Carsgen Therapeutics Limited, Shanghai, CN;
Zonghai Li, Shanghai, CN;
Huiping Gao, Shanghai, CN;
Hua Jiang, Shanghai, CN;
Bizhi Shi, Shanghai, CN;
Huamao Wang, Shanghai, CN;
Kesang Li, Shanghai, CN;
Hongyang Wang, Shanghai, CN;
Shengli Yang, Shanghai, CN;
Jianren Gu, Shanghai, CN;
CARsgen Therapeutics Limited, Shanghai, CN;
Abstract
A nucleic acid encoding a chimeric antigen receptor expressed at surface of a T lymphocyte, said chimeric antigen receptor comprises, connected in the order of, an extracellular binding domain, a transmembrane region, and an intracellular signaling domain, wherein the extracellular binding domain comprises a single chain antibody, scFv(GPC3), which specifically recognizes the C-terminal epitope of GPC3. A genetically modified T lymphocyte having a chimeric antigen receptor expressed at surface thereof, and the chimeric antigen receptor is expressed by the nucleic acid described above.