The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
May. 07, 2015
Universitaetsklinikum Jena, Jena, DE;
Alexander Mosig, Jena, DE;
Knut Rennert, Jena, DE;
Universitaetsklinikum Jena, Jena, DE;
Microfluidic ChipShop GmbH, Jena, DE;
Abstract
The invention is directed to a method for the in vitro production of arrangements of cell layers in which a first well () which is closed off from its environment except for a first inlet opening () and a first outlet opening () and which has as a first cell substrate () a first wall () and as a second cell substrate () an opposite, second wall () which is separated from the first wall () by a first gap, a free surface of a cell substrate () to be colonized with cells is oriented orthogonal to the Earth's gravitational force, and cells () are adhered to the cell substrate () to be colonized. The invention is further directed to a method of maintaining the biological functionalities of the cell layers and semi-finished products of a device for the in vitro production and culturing of cell layers and a method for the production of the device.