The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2020

Filed:

Mar. 08, 2017
Applicant:

Janssen Biotech, Inc., Horsham, PA (US);

Inventors:

Cam Holland, Spring House, PA (US);

John Kehoe, Spring House, PA (US);

Linda Snyder, Spring House, PA (US);

Alejandro Sepulveda, Spring House, PA (US);

Daniel Villarreal, Spring House, PA (US);

Assignee:

Janssen Biotech, Inc., Horsham, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61P 31/20 (2006.01); A61P 31/04 (2006.01); A61K 39/08 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 39/0011 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01);
Abstract

Provided herein are antibodies that specifically bind to GITR. Also described are related polynucleotides capable of encoding the provided GITR-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to enhance an immune response in a subject against cancer.


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