The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2020

Filed:

Aug. 08, 2017
Applicant:

National University Corporation Tokyo Medical and Dental University, Tokyo, JP;

Inventors:

Hitoshi Okazawa, Tokyo, JP;

Masunori Kajikawa, Nagoya, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); C12N 5/10 (2006.01); A61K 39/00 (2006.01); A61P 25/28 (2006.01); C12N 5/16 (2006.01); A61K 39/395 (2006.01); C07K 16/18 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C07K 16/24 (2013.01); A61K 39/395 (2013.01); A61P 25/28 (2018.01); C07K 16/18 (2013.01); C12N 5/10 (2013.01); C12N 5/16 (2013.01); C12N 15/09 (2013.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01);
Abstract

An anti-HMGB1 antibody comprising a light chain variable region comprising complementarity-determining regions or the like including amino acid sequences of SEQ ID NOs: 4 to 6, and a heavy chain variable region comprising complementarity-determining regions or the like including amino acid sequences of SEQ ID NOs: 10 to 12, or an anti-HMGB1 antibody comprising a light chain variable region or the like comprising an amino acid sequence of SEQ ID NO: 3, and a heavy chain variable region comprising an amino acid sequence or the like of SEQ ID NO: 9, and a composition for treating or preventing Alzheimer's disease, comprising the same as an active ingredient.


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