The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2020

Filed:

Sep. 28, 2015
Applicants:

University of South Carolina, Columbia, SC (US);

Musc Foundation for Research Development, Charleston, SC (US);

Inventors:

Michael John Yost, Mt. Pleasant, SC (US);

Veronica Rodriguez-Rivera, Charleston, SC (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); C07K 14/76 (2006.01); C08L 89/06 (2006.01); C08H 1/06 (2006.01); D01D 1/02 (2006.01); D01F 11/02 (2006.01); D01D 5/00 (2006.01); A61L 27/24 (2006.01); C08H 1/02 (2006.01); D01F 4/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61L 27/24 (2013.01); C07K 14/76 (2013.01); C08H 1/02 (2013.01); C08H 1/06 (2013.01); C08L 89/06 (2013.01); D01D 1/02 (2013.01); D01D 5/0046 (2013.01); D01D 5/0061 (2013.01); D01F 4/00 (2013.01); D01F 11/02 (2013.01); D10B 2211/06 (2013.01);
Abstract

Methods for reaction electrospinning are provided to form collagen fibers. The method can include: acidifying a collagen in an acidic solvent to form an acidic collagen solution; electrospinning the acidic collagen solution within an alkaline atmosphere (e.g., including ammonia vapor) to form collagen fibers; and collecting the collagen fibers within a salt bath (e.g., including ammonium sulfate). The acidic solvent can include water and an alcohol, and can have a pH of about 2 to about 4 (e.g., including a strong acid, such as HCl). An albumin rubber is also provided, which can include albumin crosslinked with glutaraldehyde.


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