The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
Apr. 06, 2016
Polyphor Ag, Allschwil, CH;
Universität Zürich, Zürich, CH;
Daniel Obrecht, Bättwil, CH;
Christian Bisang, Basel, CH;
Anatol Luther, Binzen, DE;
Steffen Weinbrenner, Constance, DE;
John Anthony Robinson, Wermatswil, CH;
Kerstin Moehle, Wettswil, CH;
Christian Steuer, Zürich, CH;
William J. Drury, III, Gothenburg, SE;
UNIVERSITAT ZURICH, Zurich, CH;
POLYPHOR AG, Allschwil, CH;
Abstract
Novel backbone-cyclized peptidomimetics of the general formulacyclo[-P-P-P-P-P-P-P-P-T-T-]   (I)wherein the single elements T or P are α-amino acid residues connected in either direction which, depending on their positions in the chain, are as defined in the description and the claims, and salts thereof, have the property to modulate the GLP-1 receptor. They can be used as medicaments to treat, prevent, or delay the onset of diseases, disorders or conditions in which modulation of the human GLP-1 receptor is beneficial, such as type 2 diabetes. These backbone-cyclized peptidomimetics can be manufactured by a process which is based on a mixed solid—and solution phase synthetic strategy.