The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
Apr. 07, 2015
Applicant:
Purdue Pharma L.p., Stamford, CT (US);
Inventors:
Stephen M. Lynch, Westfield, NJ (US);
Jiangchao Yao, Princeton, NJ (US);
Jae Hyun Park, Princeton, NJ (US);
Laykea Tafesse, Robbinsville, NJ (US);
Assignee:
Purdue Pharma L.P., Stamford, CT (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01); C07D 405/04 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 413/14 (2013.01);
Abstract
The Invention provides indole derivatives of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein R, R, A, X, Y, Z, and Ware defined as set forth in the specification. The Invention also provides the use of compounds of Formula I and the pharmaceutically acceptable salts and solvates thereof to treat pain. In certain embodiments, the Compounds of the Invention are effective in treating a disorder responsive to blockade of one or more sodium channels.