The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2020

Filed:

May. 23, 2018
Applicant:

The Government of the United States of America, As Represented BY the Secretary of the Navy, Arlington, VA (US);

Inventors:

Sean J. Hart, Keswick, VA (US);

Sarah J. R. Staton, Washington, DC (US);

Alexander V. Terray, Alexandria, VA (US);

Gregory E. Collins, Huntingtown, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/10 (2006.01); B03C 5/02 (2006.01); B81B 7/02 (2006.01); B01L 3/00 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/502715 (2013.01); B01L 3/502784 (2013.01); B81B 7/02 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0418 (2013.01); B01L 2400/0421 (2013.01); B01L 2400/0424 (2013.01); B01L 2400/0454 (2013.01); B01L 2400/0487 (2013.01); G01N 2015/1081 (2013.01);
Abstract

The combined value of integrating optical forces and electrokinetics allows for the pooled separation vectors of each to be applied, providing for separation based on combinations of features such as size, shape, refractive index, charge, charge distribution, charge mobility, permittivity, and deformability. The interplay of these separation vectors allow for the selective manipulation of analytes with a finer degree of variation. Embodiments include methods of method of separating particles in a microfluidic channel using a device comprising a microfluidic channel, a source of laser light focused by an optic into the microfluidic channel, and a source of electrical field operationally connected to the microfluidic channel via electrodes so that the laser light and the electrical field to act jointly on the particles in the microfluidic channel. Other devices and methods are disclosed.


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