The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2020

Filed:

Dec. 16, 2016
Applicant:

Vito NV, Mol, BE;

Inventors:
Assignee:

VITO NV, Mol, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 69/02 (2006.01); B01D 69/14 (2006.01); B01D 61/24 (2006.01); B01D 71/02 (2006.01); C12P 13/00 (2006.01); C07C 209/86 (2006.01); C12P 7/28 (2006.01);
U.S. Cl.
CPC ...
B01D 69/144 (2013.01); B01D 61/246 (2013.01); B01D 69/02 (2013.01); B01D 71/02 (2013.01); C07C 209/86 (2013.01); C12P 7/28 (2013.01); C12P 13/001 (2013.01); B01D 2257/70 (2013.01); B01D 2323/04 (2013.01); B01D 2323/36 (2013.01); B01D 2325/38 (2013.01);
Abstract

A membrane based process separates amines or organic acids from a solution containing at least one amine or at least one organic acid according to their hydrophobic properties. The more hydrophobic amine or organic acid passes the hydrophobic membrane into an acidic aqueous solution, thus selectively removing the amine or organic acid from the first solution. The process is particularly suitable to obtain chiral amines in high yield. A transaminase-catalyzed transamination of an amino donor and amino acceptor is combined with a hydrophobic membrane separation of the produced chiral amine. The selective removal of the chiral amine from the reaction mixture promotes the further transformation of the amino acceptor into the product chiral amine.


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