The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
May. 11, 2016
Applicant:
Imcyse SA, Liège, BE;
Inventors:
Assignee:
IMCYSE SA, Belgium, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); G01N 33/50 (2006.01); A01K 67/027 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0008 (2013.01); A01K 67/027 (2013.01); G01N 33/5088 (2013.01); A01K 2207/10 (2013.01); A01K 2227/10 (2013.01); A01K 2267/0387 (2013.01);
Abstract
The application relates to methods for determining a parameter such as toxicity and pharmacokinetic behavior for a pharmaceutical compound against a disease or disorder. The test animals being used are non-human animals not suffering from or is not showing symptoms or signs of the disorder and which do not provoke an immune response against said pharmaceutical compound. These animals are obtainable by administration of a peptide comprising an oxidoreductase motif further comprising an NKT peptide epitope or an MHC class II T cell epitope of said pharmaceutical compound, wherein said motif and said epitope are separated by a linker of between 0 and 4 amino acids.