The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
Dec. 19, 2016
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Matthew Weiss, Boston, MA (US);
Thomas Dineen, Arlington, MA (US);
Karina R. Vaida, Burlington, MA (US);
Assignee:
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/36 (2006.01); A61K 31/4704 (2006.01); C07D 241/44 (2006.01); C07D 403/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 413/12 (2006.01); A61P 29/02 (2006.01); A61P 11/14 (2006.01); A61K 31/501 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4704 (2013.01); A61K 31/501 (2013.01); A61P 11/14 (2018.01); A61P 29/02 (2018.01); C07D 215/36 (2013.01); C07D 241/44 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01);
Abstract
The present invention provides compounds of Formula I, and pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases associated with the activity of sodium channels such as pain disorders, cough, and itch. Also provided are pharmaceutical compositions containing compounds of the present invention.