The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
Feb. 06, 2019
Applicant:
Revogenex Ireland Ltd, Dublin, IE;
Inventors:
Assignee:
Revogenex Ireland Ltd., Dublin, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/135 (2006.01); A61P 25/04 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/135 (2013.01); A61P 25/00 (2018.01); A61P 25/04 (2018.01);
Abstract
A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously in a dosing regimen which includes one or more loading doses administered at shortened intervals as compared to dosing at steady-state is disclosed. In preferred embodiments, the intravenous dosing regimen provides a Cmax and AUC of tramadol is similar to the Cmax and AUC of an oral dose of 100 mg tramadol HC1 given every 6 hours.