The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

Nov. 27, 2017
Applicants:

New York University, New York, NY (US);

Siemens Healthcare Gmbh, Erlangen, DE;

Inventors:

Martijn Cloos, Long Island City, NY (US);

Tom Hilbert, Lausanne, CH;

Tobias Kober, Lausanne, CH;

Assignees:

Siemens Healthcare GmbH, Erlangen, DE;

New York University, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/48 (2006.01); G01R 33/56 (2006.01); G01R 33/50 (2006.01);
U.S. Cl.
CPC ...
G01R 33/4828 (2013.01); G01R 33/5605 (2013.01); G01R 33/5608 (2013.01); G01R 33/50 (2013.01);
Abstract

In a magnetic resonance (MR) apparatus, and model-based method, for identifying a nuclear spin-dependent attribute of a subject, MR signals are acquired in multiple repetitions of an MR data acquisition sequence that is changed from repetition-to-repetition so as to deliberately encode effects of magnetization transfer between nuclear spins into the acquired MR signals. A model is generated, composed of at least two molecule pools, in which a single magnetization transfer parameter is used that is derived from the MR signals in which the magnetization transfer is encoded. A nuclear spin-dependent attribute of the subject is then identified, by comparing at least one MR signal evolution from the subject to at least one signal evolution produced by the model.


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