The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Apr. 08, 2015
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
The Research Foundation for State University of New York, Albany, NY (US);
Kevin Ka-Wang Wang, Gainesville, FL (US);
Zhihui Yang, Gainesville, FL (US);
Ahmed Moghieb, Richland, WA (US);
Richard Rubenstein, Staten Island, NY (US);
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
The Research Foundation For The State University of New York, Albany, NY (US);
Abstract
Proteins that are differentially expressed or elevated in tissue and biofluids after central nervous system injuries are described. Elevated or reduced levels of the proteins, alone or in various combinations or ratios, can be used to assess severity of central nervous system injury (CNS injury) including traumatic brain injury (TBI), traumatic spinal cord injury (SCI) and chronic traumatic encephalopathy (CTE). Time course measurements post CNS-injury of these proteins can be used to monitor progress or recovery over periods up to several months. Differentiation of acute, subacute and chronic injury can be diagnosed by comparing the protein levels in CNS-injury patients at days 1-3, day 4-10 with levels at day 30-180 in comparison with normal controls.