The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

May. 22, 2013
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventor:

Stanton Gerson, Hunting Valley, OH (US);

Assignee:

CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/131 (2006.01); G01N 33/573 (2006.01); A61P 35/00 (2006.01); A61K 31/513 (2006.01); A61K 31/7076 (2006.01); A61K 45/06 (2006.01); G01N 33/574 (2006.01); A61K 31/517 (2006.01); A61K 31/7072 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); A61K 31/131 (2013.01); A61K 31/513 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/7072 (2013.01); A61K 31/7076 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12Y 302/02027 (2013.01); G01N 33/574 (2013.01); G01N 2333/926 (2013.01); G01N 2800/52 (2013.01);
Abstract

A method of determining the susceptibility of a cancer in a subject to treatment with an antimetabolite includes obtaining a sample of cancer cells from the subject, measuring the level of UDG expression in the cancer cells, and comparing the measured levels of UDG expression in the cancer cells to a control level.


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