The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Dec. 13, 2013
Applicant:
Research Development Foundation, Carson City, NV (US);
Inventors:
George Georgiou, Austin, TX (US);
Sang Taek Jung, Seoul, KR;
Assignee:
Research Development Foundation, Carson City, NV (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); C07K 16/32 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56911 (2013.01); C07K 16/00 (2013.01); C07K 16/32 (2013.01); C07K 2317/52 (2013.01); C07K 2317/72 (2013.01); C07K 2319/035 (2013.01); C07K 2319/30 (2013.01);
Abstract
Methods and composition for the screening and isolation of aglycosylated antibody Fc domain polypeptides. For example, in certain aspects methods for identifying aglycosylated Fc domains that bind to Fc receptors or preferentially bind to particular Fc receptors are described. Furthermore, the invention provides aglycosylated Fc domains that bind to Fc receptors with high affinity. Enhanced methods and media for prokaryotic based interaction screening are also provided.