The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

Nov. 02, 2017
Applicants:

Regents of the University of Minnesota, Minneapolis, MN (US);

The Governing Council of the University of Toronto, Toronto, CA;

Inventors:

John C. Bischof, St. Paul, MN (US);

Zhenpeng Qin, Allen, TX (US);

Warren Chan, Toronto, CA;

Taner Akkin, Arden Hills, MN (US);

Li Zhan, Minneapolis, MN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/558 (2006.01); G01N 33/569 (2006.01); G01N 33/76 (2006.01); G01N 25/48 (2006.01); G01N 21/77 (2006.01); G01N 21/17 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54393 (2013.01); G01N 21/171 (2013.01); G01N 21/77 (2013.01); G01N 25/488 (2013.01); G01N 33/558 (2013.01); G01N 33/5695 (2013.01); G01N 33/56905 (2013.01); G01N 33/56961 (2013.01); G01N 33/76 (2013.01); G01N 2021/1714 (2013.01); G01N 2333/35 (2013.01); G01N 2333/39 (2013.01); G01N 2333/445 (2013.01); G01N 2333/59 (2013.01); Y02A 50/58 (2018.01);
Abstract

Assays used in conjunction with a thermal contrast reader are disclosed. In the assay, the test strip includes materials that can develop a thermal response if a target analyte is present in a sample. Linear flow assays include nanoparticles with high affinity binding to the analyte. Binding of the nanoparticles with an analyte in the sample is detected using thermal contrast. Analytes over a broad range of concentrations are detected in the linear flow assays. Methods of detecting target analytes and kits comprising lateral flow assays and thermal contrast reader are also disclosed.


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