The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

Apr. 04, 2019
Applicant:

10x Genomics, Inc., Pleasanton, CA (US);

Inventors:

Jason Bell, Palo Alto, CA (US);

Geoffrey McDermott, Livermore, CA (US);

Francesca Meschi, Menlo Park, CA (US);

Michael Schnall-Levin, San Francisco, CA (US);

Xinying Zheng, San Jose, CA (US);

Assignee:

10X GENOMICS, INC., Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/532 (2006.01); G01N 33/543 (2006.01); G01N 33/548 (2006.01); C12N 15/10 (2006.01); C12Q 1/6804 (2018.01); C12Q 1/6806 (2018.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/58 (2006.01); C12Q 1/6818 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6881 (2018.01); C12N 15/11 (2006.01); G01N 33/569 (2006.01); C40B 70/00 (2006.01); C07K 14/74 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
G01N 33/532 (2013.01); C07K 14/70539 (2013.01); C12N 15/1037 (2013.01); C12N 15/1055 (2013.01); C12N 15/1065 (2013.01); C12N 15/1075 (2013.01); C12N 15/11 (2013.01); C12N 15/85 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6818 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6881 (2013.01); G01N 33/505 (2013.01); G01N 33/5032 (2013.01); G01N 33/5304 (2013.01); G01N 33/5306 (2013.01); G01N 33/5308 (2013.01); G01N 33/548 (2013.01); G01N 33/54306 (2013.01); G01N 33/54366 (2013.01); G01N 33/56977 (2013.01); G01N 33/58 (2013.01); C12N 2310/20 (2017.05); C12N 2320/10 (2013.01); C12Q 2537/164 (2013.01); C12Q 2563/179 (2013.01); C12Q 2563/185 (2013.01); C12Q 2565/1015 (2013.01); C40B 70/00 (2013.01);
Abstract

The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization from a single cell. Such polynucleotide processing may be useful for a variety of applications. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins) and chromatin (e.g., accessible chromatin).


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