The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

Oct. 09, 2013
Applicant:

Curiox Biosystems Pte Ltd., Singapore, SG;

Inventors:

Kong Leong Cheng, Singapore, SG;

Siah Chong Cheong, Singapore, SG;

Namyong Kim, Allston, MA (US);

Eng Seng Lim, Singapore, SG;

Hanwen Melvin Lye, Singapore, SG;

Zhong Wang, Singapore, SG;

Wan Yee Leong, Boston, MA (US);

Mark S. Phong, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12N 15/10 (2006.01); B01L 3/00 (2006.01); G01N 33/543 (2006.01); G01N 35/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5008 (2013.01); B01L 3/5088 (2013.01); C12N 15/1082 (2013.01); G01N 33/54373 (2013.01); B01L 3/5085 (2013.01); B01L 13/02 (2019.08); B01L 2300/0609 (2013.01); B01L 2300/089 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/161 (2013.01); B01L 2400/0415 (2013.01); G01N 2035/1037 (2013.01);
Abstract

The present invention provides an apparatus for conducting biological assays which employs 'virtual wells' in lieu of the physical wells of conventional array plates. Also provided are methods of processing a sample and/or culturing cells using the apparatus and systems described herein. In some embodiments, the apparatus includes a first structure having a sheet layer with a plurality of discrete through holes; and a second structure coupled to the first structure, the second structure including a base layer. At least a portion of a first surface of the sheet layer of the first structure is exposed from the second structure, and a second surface of the sheet layer, opposite to the first surface of the sheet layer, is embedded in the base layer of the second structure adjacent the first surface of the base layer.


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