The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

Dec. 15, 2016
Applicants:

Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;

Assistance Publique-hôpitaux DE Paris (Aphp), Paris, FR;

Université Paris-est Créteil Val DE Marne, Creteil, FR;

Inventors:

Sophie Hue, Créteil, FR;

Yves Levy, Créteil, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12Q 1/6876 (2018.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); G01N 33/6893 (2013.01); C12Q 2600/106 (2013.01); G01N 2333/4737 (2013.01); G01N 2333/5412 (2013.01); G01N 2333/70596 (2013.01); G01N 2800/24 (2013.01); G01N 2800/26 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention provides diagnostic markers of immunosenescence and methods of identifying individuals with impaired immune function based on the expression level of a combination of such markers in a biological sample obtained from said individual. Such combination of markers is useful for determining the susceptibility to nosocomial infections of an individual. Such combination of markers is also useful for predicting whether an individual will respond to active vaccination and become protected against recurring diseases.


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