The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Jun. 07, 2019
Applicant:
Pharmazell Gmbh, Raubling, DE;
Inventors:
Werner Hummel, Titz, DE;
Daniel Bakonyi, Cologne, DE;
Assignee:
Pharmazell GmbH, Raubling, DE;
Primary Examiner:
Int. Cl.
CPC ...
C12P 33/02 (2006.01); C12N 9/00 (2006.01); C12N 9/04 (2006.01);
U.S. Cl.
CPC ...
C12P 33/02 (2013.01); C12N 9/0006 (2013.01); C12Y 101/01201 (2013.01);
Abstract
The invention relates to novel 7β-hydroxysteroid dehydrogenase mutants, to the sequences which code for these enzyme mutants, to processes for the preparation of the enzyme mutants and to their use in enzymatic conversions of cholic acid compounds, in particular in the preparation of ursodeoxycholic acid (UDCA); subject-matter of the invention is also novel processes for the synthesis of UDCA using enzyme mutants; and the preparation of UDCA using recombinant, multiply modified microorganisms.