The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Mar. 18, 2016
Applicant:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Inventors:
Nasim Annabi, Cambridge, MA (US);
Ali Khademhosseini, Cambridge, MA (US);
Assignee:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/78 (2006.01); A61L 24/10 (2006.01); A61L 26/00 (2006.01); A61L 24/00 (2006.01); A61L 27/22 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61L 24/0015 (2013.01); A61L 24/0031 (2013.01); A61L 24/108 (2013.01); A61L 26/008 (2013.01); A61L 26/0047 (2013.01); A61L 26/0066 (2013.01); A61L 27/227 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 2300/404 (2013.01); A61L 2300/418 (2013.01); A61L 2300/64 (2013.01); A61L 2400/04 (2013.01);
Abstract
Disclosed herein are polypeptides comprising an amino acid sequence of {[VPGVG]IPGVG}, wherein n is an integer greater than 1. The polypeptides can be crosslinked to from biocompatible hydrogels with tunable and desirable mechanical properties. The polypeptides and hydrogels can be used in a variety of biomedical applications including treatment of bleeding, treatment of soft tissue injury, injectable filler, and tissue adhesives.