The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

May. 20, 2016
Applicants:

Xiamen University, Xiamen, Fujian Province, CN;

Xiamen Innovax Biotech Co., Ltd., Xiamen, Fujian, CN;

Inventors:

Shengxiang Ge, Fujian, CN;

Tingdong Li, Fujian, CN;

Lianzhi Jia, Fujian, CN;

Yijian Li, Fujian, CN;

Miaoge Xue, Fujian, CN;

Yuanjun Zeng, Fujian, CN;

Huirong Pan, Fujian, CN;

Jun Zhang, Fujian, CN;

Ningshao Xia, Fujian, CN;

Assignees:

Xiamen University, Xiamen, Fujian, CN;

Xiamen Innovax Biotech Co., Ltd., Xiamen, Fujian, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); A61K 39/15 (2006.01); A61P 31/14 (2006.01); A61P 1/12 (2006.01); A61P 1/00 (2006.01); A61P 29/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61K 39/15 (2013.01); A61P 1/00 (2018.01); A61P 1/12 (2018.01); A61P 29/00 (2018.01); A61P 31/14 (2018.01); C12N 7/00 (2013.01); A61K 2039/552 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/575 (2013.01); C12N 2720/12322 (2013.01); C12N 2720/12334 (2013.01); C12N 2720/12351 (2013.01);
Abstract

The invention relates to a truncated rotavirus VP4 protein, a sequence encoding the same, a method for preparing the same, and a pharmaceutical composition and a vaccine comprising the protein, wherein the protein, the pharmaceutical composition and the vaccine are useful for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea. The invention further relates to use of the protein in the manufacture of a pharmaceutical composition or a vaccine for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea.


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