The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2020

Filed:

Sep. 06, 2016
Applicant:

Biophore India Pharmaceuticals Pvt. Ltd., Hyderabad, IN;

Inventors:

Manik Reddy Pullagurla, Hyderabad, IN;

Mecheril Valsan Nanda Kumar, Hyderabad, IN;

Bhaskar Reddy Pitta, Hyderabad, IN;

Suresh Babu Namana, Hyderabad, IN;

Jagadeesh Babu Rangisetty, Hyderabad, IN;

Sadashiv Choppari, Hyderabad, IN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 303/00 (2006.01); C07F 1/04 (2006.01); C07C 303/04 (2006.01); C07C 303/44 (2006.01); C07C 303/22 (2006.01); C07C 303/06 (2006.01);
U.S. Cl.
CPC ...
C07F 1/04 (2013.01); C07C 303/00 (2013.01); C07C 303/04 (2013.01); C07C 303/06 (2013.01); C07C 303/22 (2013.01); C07C 303/44 (2013.01); C07B 2200/13 (2013.01);
Abstract

Provided is an improved process for the preparation N-[4-[[4-(diethyl amino) phenyl](2,5-disulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-N-ethylethanaminium inner salt sodium salt (Isosulfan blue) of formula I. It also relates to highly pure novel crystalline form of Isosulfan blue hydrate and its process for the preparation thereof. It also relates to an improved process for the preparation of Isosulfan blue sodium hydrate having not more than 0.2% of desethyl impurity of formula A.


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