The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Jan. 27, 2017
Applicants:
Pfizer Inc., New York, NY (US);
Covx Technologies Ireland Limited, Ringaskiddy, Co. Cork, IE;
Inventors:
Chakrapani Subramanyam, South Glastonbury, CT (US);
Lawrence N. Tumey, Vestal, NY (US);
Longfei Xie, Groton, CT (US);
Carolyn Leverett, Groton, CT (US);
Beth C. Vetelino, North Stonington, CT (US);
Sai Chetan K. Sukuru, Glastonbury, CT (US);
Sarah Hudson, San Diego, CA (US);
Venkata Ramana Doppalapudi, San Dieto, CA (US);
Abhijit S. Bhat, Winchester, MA (US);
Assignee:
Pfizer Inc., New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 31/427 (2006.01); A61K 31/4025 (2006.01); A61K 47/65 (2017.01); C07D 277/56 (2006.01); C07D 417/12 (2006.01); A61P 35/00 (2006.01); C07D 277/42 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 47/65 (2017.08); A61K 47/6803 (2017.08); A61P 35/00 (2018.01); C07D 277/42 (2013.01); C07D 277/56 (2013.01);
Abstract
The present invention is directed to novel cytotoxic tubulysin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.