The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Jul. 19, 2018
Applicant:
Ohio State Innovation Foundation, Columbus, OH (US);
Inventors:
Robert A. Baiocchi, Dublin, OH (US);
Chenglong Li, Dublin, OH (US);
Hongshan Lai, Columbus, OH (US);
Said Sif, Dublin, OH (US);
Assignee:
The Ohio State University, Columbus, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/82 (2006.01); C07D 209/86 (2006.01); C07D 209/88 (2006.01);
U.S. Cl.
CPC ...
C07D 209/82 (2013.01); C07D 209/86 (2013.01); C07D 209/88 (2013.01);
Abstract
The disclosure relates to PRMT5 inhibitors, including optionally substituted N-alkyl-9H-carbazole analogs, derivatives thereof, and related compounds; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation and benign hematologic diseases using the compounds and compositions.