The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Nov. 20, 2015
Applicant:
Phasebio Pharmaceuticals, Inc., Malvern, PA (US);
Inventors:
James Jowett, Malvern, PA (US);
David James Ballance, Malvern, PA (US);
Assignee:
PHASEBIO PHARMACEUTICALS, INC., Malvern, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61K 38/14 (2006.01); A61K 38/26 (2006.01); A61K 38/27 (2006.01); A61K 38/28 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 47/02 (2006.01); A61K 9/08 (2006.01); A61P 35/00 (2006.01); A61K 31/196 (2006.01); A61K 31/277 (2006.01); A61K 31/337 (2006.01); A61K 31/475 (2006.01); A61K 31/704 (2006.01); C07K 16/26 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6435 (2017.08); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 38/14 (2013.01); A61K 38/26 (2013.01); A61K 38/27 (2013.01); A61K 38/28 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/64 (2017.08); A61P 35/00 (2018.01); A61K 31/196 (2013.01); A61K 31/277 (2013.01); A61K 31/337 (2013.01); A61K 31/475 (2013.01); A61K 31/704 (2013.01); A61K 2300/00 (2013.01); C07K 16/26 (2013.01); C07K 16/28 (2013.01);
Abstract
The present disclosure provides pharmaceutical formulations for sustained release, and methods for delivering a treatment regimen with a combination of sustained release and long half-life formulations. The pharmaceutical formulations comprise a therapeutic agent including an active agent and an amino acid sequence capable of forming a reversible matrix at the body temperature of a subject. The disclosure provides improved pharmacokinetics for peptide and small molecule drugs.