The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Sep. 29, 2017
Applicant:
Sri International, Menlo Park, CA (US);
Inventors:
Thomas R. Webb, Mountain View, CA (US);
Jaehyeon Park, Sunnyvale, CA (US);
Chandraiah Lagisetti, Cupertino, CA (US);
Assignee:
SRI International, Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/522 (2006.01); A61K 31/52 (2006.01); A61P 35/00 (2006.01); C07D 473/32 (2006.01); C07D 473/16 (2006.01); A61K 31/437 (2006.01);
U.S. Cl.
CPC ...
A61K 31/52 (2013.01); A61K 31/437 (2013.01); A61P 35/00 (2018.01); C07D 473/16 (2013.01); C07D 473/32 (2013.01);
Abstract
The disclosure generally relates to substituted purine analogs that are dual CLK2/CDK1 inhibitors or more potent and specific CLK inhibitors to target CLK2 and CDK1 kinases. These compounds may be useful in the treatment of germ-line mutations of the spliceosome leading to the development of cancers and other human disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.