The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2020
Filed:
Jul. 13, 2015
Applicant:
Chugai Seiyaku Kabushiki Kaisha, Gotemba-shi, Shizuoka, JP;
Inventors:
Assignee:
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/68 (2006.01); A61K 38/00 (2006.01); C12P 21/02 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); C12Q 1/02 (2006.01); C12N 5/10 (2006.01); C07K 14/415 (2006.01); C07K 14/755 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); A61K 38/00 (2013.01); C07K 7/00 (2013.01); C07K 14/00 (2013.01); C07K 14/415 (2013.01); C07K 14/755 (2013.01); C07K 16/241 (2013.01); C12N 5/10 (2013.01); C12P 21/02 (2013.01); C12Q 1/02 (2013.01); C07K 2317/24 (2013.01);
Abstract
In one aspect, the present invention provides, for example, an improved method for identifying an epitope on a protein, comprising the following steps: (A) contacting a major histocompatibility complex (MHC molecule)-expressing cell differentiated from a stem cell or a progenitor cell derived therefrom with a target protein; (B) isolating a complex of a peptide contained in the target protein and the MHC molecule from the MHC molecule-expressing cell; and (C) eluting the peptide from the complex and identifying the peptide.