The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2020

Filed:

Oct. 27, 2017
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Peter Burke, Irvine, CA (US);

Ted Pham, Westminster, CA (US);

Phi Pham, Irvine, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 27/414 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5079 (2013.01); G01N 27/4145 (2013.01); G01N 33/5438 (2013.01);
Abstract

Mitochondria are central to the intrinsic apoptotic pathway of programmed cell death. Commitment to cell death occurs upon mitochondrial outer membrane permeabilization, and dysregulation of this vital apoptotic control point is implicated in various pathologies. Provided herein are novel sensors which can detect, in real time and with great sensitivity, the release of protons from intact mitochondria caused by mitochondrial outer membrane permeabilization. Embodiments include graphene based ion-sensitive field effect transistors.


Find Patent Forward Citations

Burke, Peter. (2020). Mitochondrial apoptotic sensor (U.S. Patent No. 10718756). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10718756

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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