The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2020

Filed:

Dec. 04, 2014
Applicant:

Korea Hydro & Nuclear Power Co., Ltd., Gyeongju-si, Gyeongsangbuk-do, KR;

Inventors:

Hee Sun Kim, Uijeongbu-si, KR;

Dong Kwon Keum, Daejeon, KR;

Hoon Choi, Seoul, KR;

Kwang Hee Yang, Seoul, KR;

Hyun Soon Bang, Uijeongbu-si, KR;

Assignee:

Korea Hydro & Nuclear Power Co., Ltd., Gyeongju-si, Gyeongsangbuk-do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01); C12Q 1/686 (2018.01); C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/142 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Disclosed is a detection method for DNA repair-related genes which respond to low-level radiation, which includes the steps of (1) breeding AKR/J mice, as a thymus cancer model, and normal ICR mice in a low-dose radiation environment; (2) collecting thymuses from the AKR/J thymus cancer mouse model and the normal ICR mice which have been bred at the step (1); (3) analyzing genes in the thymuses collected at the step (2); (4) detecting, among the genes analyzed at the step (3), a DNA repair-associated gene expressed commonly or differentially in the AKR/J thymus cancer mouse model and the normal ICR mice; and (5) amplifying the gene detected at the step (4) and measuring the expression level thereof.


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