The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2020

Filed:

May. 28, 2015
Applicants:

Georgetown University, Washington, DC (US);

University of Rochester, Rochester, NY (US);

Inventors:

Massimo S. Fiandaca, Millersville, MD (US);

Mark E. Mapstone, Pittsford, NY (US);

Yuriy Gusev, North Bethesda, MD (US);

Howard J. Federoff, Bethesda, MD (US);

Assignees:

GEORGETOWN UNIVERSITY, Washington, DC (US);

UNIVERSITY OF ROCHESTER, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12Q 1/68 (2018.01); G01N 33/567 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6876 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 1/6876 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01);
Abstract

The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing the gene expression profile from peripheral blood leukocytes taken from the subject and comparing the value of the subject's gene expression profile with the value of a normal gene expression profile. A change in the value of the subject's gene expression profile, above or below normal values is indicative that the subject has an increased risk of suffering from memory impairment compared to a normal individual.


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