The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2020

Filed:

Dec. 15, 2016
Applicant:

Agricultural Technology Research Institute, Hsinchu, TW;

Inventors:

Chin-Kai Chuang, Hsinchu, TW;

Yu-Hsiu Su, Hsinchu, TW;

Tzuyin Lin, Hsinchu, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/04 (2006.01); A61K 47/64 (2017.01); C12N 15/09 (2006.01); C12N 15/87 (2006.01); C07K 14/245 (2006.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); A61K 47/64 (2017.08); C07K 14/245 (2013.01); C07K 2319/10 (2013.01);
Abstract

The invention provides a recombinant polypeptide X—Y for enhancing cell transduction efficiency of a target agent, wherein X is a cell penetrating peptide DPV3, and Y is an Hsp40-J domain. Also provided is a method for enhancing cell transduction efficiency of a target agent, comprising conjugating/attaching said target agent with a recombinant polypeptide X—Y, wherein X is a cell penetrating peptide DPV3, and Y is an Hsp40-J domain. Further provided is a pharmaceutical composition comprising a therapeutic agent, wherein said therapeutic agent is modified by conjugating/attaching with a recombinant polypeptide X—Y, wherein X is a cell penetrating peptide DPV3, and Y is an Hsp40-J domain.


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