The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2020
Filed:
Jun. 19, 2019
Applicant:
Unity Biotechnology, Inc., Brisbane, CA (US);
Inventors:
Anne-Marie Beausoleil, Brisbane, CA (US);
Ryan Hudson, Brisbane, CA (US);
Assignee:
Unity Biotechnology, Inc., Brisbane, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/337 (2006.01); C07D 401/12 (2006.01); C07D 401/10 (2006.01); C07D 403/10 (2006.01); A61P 9/10 (2006.01); A61P 35/00 (2006.01); A61P 27/00 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/10 (2013.01); A61P 9/10 (2018.01); A61P 27/00 (2018.01); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01);
Abstract
The aryl sulfonamide compounds of this invention have powerful and cell-type specific Bcl inhibitory activity. Compounds of this invention include compounds according to formula (I): Selected compounds in this class promote apoptosis in senescent cells, and are being developed for treating senescent-related conditions. Selected compounds in this class promote apoptosis in cancer cells, and can be developed as chemotherapeutic agents.