The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2020

Filed:

Sep. 01, 2014
Applicant:

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Motoichi Kurisawa, Singapore, SG;

Ki Hyun Bae, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 9/06 (2006.01); A61K 8/73 (2006.01); A61K 8/49 (2006.01); A61K 9/00 (2006.01); A61K 31/353 (2006.01); A61K 8/04 (2006.01); A61Q 19/00 (2006.01); C07D 311/32 (2006.01); A61K 8/81 (2006.01); A61K 47/61 (2017.01); A61K 47/36 (2006.01); A61K 47/32 (2006.01);
U.S. Cl.
CPC ...
A61Q 19/00 (2013.01); A61K 8/042 (2013.01); A61K 8/498 (2013.01); A61K 8/735 (2013.01); A61K 8/8147 (2013.01); A61K 9/0019 (2013.01); A61K 9/06 (2013.01); A61K 31/353 (2013.01); A61K 47/61 (2017.08); C07D 311/32 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01); A61K 2800/57 (2013.01); A61K 2800/91 (2013.01);
Abstract

There is provided polymer-flavonoid conjugates. Flavonoid-grafted and flavonoid-terminated polymer conjugates are disclosed according to the invention. The linkage of flavonoids to the polymers has been achieved via thiol linkages. The inventive processes allow for making of the conjugates in high yield avoiding complex purification steps. The conjugates can be easily autoxidized to hydrogels with uses in many biomedical applications where a higher stability of the flavonoid is necessary. The hydrogels can be potentially used as viscosupplement, anti-adhesion film or dermal filler.


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